Abstract
The well-known adjuvant action of the homoribopolymer complex, polyadenylic-polyuridylic acid (poly A:U) was extended to an in vitro system utilizing human peripheral blood leucocytes (PBL) and tonsillar tissue. IgG synthesis by PBL plaque-forming cell and (PFC) formation by tonsillar tissue were enhanced by poly A:U. In addition, natural cytotoxicity by PBL against the human myeloid cell line K-562 was increased by this nontoxic adjuvant and was markedly stimulated by the removal of an adherent cell population.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 643-653 |
| Number of pages | 11 |
| Journal | RES Journal of the Reticuloendothelial Society |
| Volume | 26 |
| Issue number | SUPPL. |
| State | Published - 1979 |