Stimulated growth of human and pig epidermal nerve fibers by tape stripping

Mona M. Selim; Kathy A. Wabner; Gwen Wendelschafer-Crabb; William R. Kennedy

doi:10.1007/s00403-007-0791-4

Stimulated growth of human and pig epidermal nerve fibers by tape stripping

Mona M. Selim, Kathy A. Wabner, Gwen Wendelschafer-Crabb, William R. Kennedy

Neurology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Nerve growth studies in adults usually rely upon nerve regeneration that follows axon disruption. In this study elongation of the epidermal nerve fibers occurred in human and pig epidermis stimulated to hypertrophy by removing the stratum corneum with repetitive applications of tape (tape stripping). Epidermal thickening was accompanied by elongation of the epidermal nerve fibers. This study demonstrates that changing the cellular and chemical environment of nerves by tape stripping is a feasible method to study nerve fiber growth in a physiological manner.

Original language	English (US)
Pages (from-to)	513-516
Number of pages	4
Journal	Archives of Dermatological Research
Volume	299
Issue number	10
DOIs	https://doi.org/10.1007/s00403-007-0791-4
State	Published - Dec 2007

Bibliographical note

Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.

Keywords

Immunohistochemistry
Nerve growth
PGP 9.5
Tape stripping

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abstract = "Nerve growth studies in adults usually rely upon nerve regeneration that follows axon disruption. In this study elongation of the epidermal nerve fibers occurred in human and pig epidermis stimulated to hypertrophy by removing the stratum corneum with repetitive applications of tape (tape stripping). Epidermal thickening was accompanied by elongation of the epidermal nerve fibers. This study demonstrates that changing the cellular and chemical environment of nerves by tape stripping is a feasible method to study nerve fiber growth in a physiological manner.",

keywords = "Immunohistochemistry, Nerve growth, PGP 9.5, Tape stripping",

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AU - Selim, Mona M.

AU - Wabner, Kathy A.

AU - Wendelschafer-Crabb, Gwen

AU - Kennedy, William R.

PY - 2007/12

Y1 - 2007/12

N2 - Nerve growth studies in adults usually rely upon nerve regeneration that follows axon disruption. In this study elongation of the epidermal nerve fibers occurred in human and pig epidermis stimulated to hypertrophy by removing the stratum corneum with repetitive applications of tape (tape stripping). Epidermal thickening was accompanied by elongation of the epidermal nerve fibers. This study demonstrates that changing the cellular and chemical environment of nerves by tape stripping is a feasible method to study nerve fiber growth in a physiological manner.

AB - Nerve growth studies in adults usually rely upon nerve regeneration that follows axon disruption. In this study elongation of the epidermal nerve fibers occurred in human and pig epidermis stimulated to hypertrophy by removing the stratum corneum with repetitive applications of tape (tape stripping). Epidermal thickening was accompanied by elongation of the epidermal nerve fibers. This study demonstrates that changing the cellular and chemical environment of nerves by tape stripping is a feasible method to study nerve fiber growth in a physiological manner.

KW - Immunohistochemistry

KW - Nerve growth

KW - PGP 9.5

KW - Tape stripping

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JO - Archives of Dermatological Research

JF - Archives of Dermatological Research

SN - 0340-3696

IS - 10

ER -

Stimulated growth of human and pig epidermal nerve fibers by tape stripping

Abstract

Bibliographical note

Keywords

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