Sterol dynamics following portacaval shunt

John J. Coyle, Ignacio J. Guzman, Russell Hanson, Richard L. Varco, Henry Buchwald

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


This study reports lipid studies on dogs up to 44 weeks following portacaval shunt. We have shown portacaval shunt to be associated with significant decreases in plasma cholesterol and triglyceride levels in the dog. Cholesterol synthesis and absorption appear to be unchanged following operation when compared to control animals. Two-hour postprandial serum bile acids are fortyfold greater in shunted animals than in control dogs. Further studies of the interrelationship of bile acid and cholesterol metabolism following portacaval shunt are suggested.

Original languageEnglish (US)
Pages (from-to)348-351
Number of pages4
JournalJournal of Surgical Research
Issue number4
StatePublished - Apr 1977

Bibliographical note

Funding Information:
1 Supported in part by grants from the National Heart and Lung Institute (HL 11901 and HL 15265).


Dive into the research topics of 'Sterol dynamics following portacaval shunt'. Together they form a unique fingerprint.

Cite this