Stereochemistry of the Cyclization of the Half-Esters of Diarylitaeonic Acid

E. E. Smissman, P. S. Portoghese, R. A. Mode

Research output: Contribution to journalArticle


The stereochemistry of the products obtained by the Stobbe condensation of 3,4-methylenedioxy-3′,4′,5′-trimethoxybenzophenone with dimethyl succinate and the dihydro-Stobbe products is proven. The conformational implications derived by a study of the cyclization of the dihydro-Stobbe products are discussed.

Original languageEnglish (US)
Pages (from-to)3628-3631
Number of pages4
JournalJournal of Organic Chemistry
Issue number10
StatePublished - Oct 1961


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