Stereo- and enantio-controlled synthesis of chiral intermediates for the total synthesis of thienamycin and related β-lactam antibiotics from 3-hydroxybutyrates

Gunda I. Georg, Harpal S. Gill

Research output: Contribution to journalArticle

19 Scopus citations

Abstract

The synthesis of (1′R,3S,4S)- and (1′R,3S,4R)-3-(1′-t- butyldimethylsilyloxyethyl)-4-hydroxymethyl-2-azetidinone from ethyl (S)-3-hydroxybutyrate is reported.

Original languageEnglish (US)
Pages (from-to)1433-1435
Number of pages3
JournalJournal of the Chemical Society, Chemical Communications
Issue number20
DOIs
StatePublished - Jan 1 1985

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