Stenting of ductus venosus as a palliation for portal hypertension because of neonatal cirrhosis

Nicholas Brown, Heli Bhatt, Amrita Salunke, Srinath Chinnakotla, Athar M. Qureshi, Varun Aggarwal

Research output: Contribution to journalArticlepeer-review

Abstract

Portal hypertension because of liver cirrhosis is a significant cause of morbidity and mortality. Treatment options in these patients include liver transplant, symptomatic treatment of oesophageal varices via endoscopic treatment and symptomatic management of ascites. Portosystemic shunt creation can be challenging in newborns and infants. We present a newborn with Trisomy 21, severe portal hypertension secondary to neonatal cirrhosis, oesophageal varices and upper GI bleeding, severe ascites refractory to medical management who underwent ductus venosus stenting as a palliative procedure. He demonstrated remarkable clinical improvement with no subsequent upper GI bleed and resolution of ascites till his last follow-up at 12 months of age. To the best of our knowledge, stenting of the patent ductus venosus to create a portosystemic shunt to relieve portal hypertension has not been reported in English literature.

Original languageEnglish (US)
Pages (from-to)879-883
Number of pages5
JournalLiver International
Volume42
Issue number4
DOIs
StatePublished - Apr 2022

Bibliographical note

Publisher Copyright:
© 2022 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Keywords

  • ductus venosus
  • neonatal cirrhosis
  • portal hypertension
  • stent

PubMed: MeSH publication types

  • Journal Article

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