Stem cells, cell therapies, and bioengineering in lung biology and disease 2021

Laertis Ikonomou, Mattias Magnusson, Ruben Dries, Erica L. Herzog, Robert E. Hynds, Zea Borok, Jin Ah Park, Steven Skolasinski, Janette K. Burgess, Leigh Turner, Sarah M. Mojarad, John E. Mahoney, Thomas Lynch, Mareike Lehmann, Victor J. Thannickal, Jamie L. Hook, Andrew E. Vaughan, Evan T. Hoffman, Daniel J. Weiss, Amy L. Ryan

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


The 9th biennial conference titled “Stem Cells, Cell Therapies, and Bioengineering in Lung Biology and Diseases” was hosted virtually, due to the ongoing COVID-19 pandemic, in collaboration with the University of Vermont Larner College of Medicine, the National Heart, Lung, and Blood Institute, the Alpha-1 Foundation, the Cystic Fibrosis Foundation, and the International Society for Cell & Gene Therapy. The event was held from July 12th through 15th, 2021 with a pre-conference workshop held on July 9th. As in previous years, the objectives remained to review and discuss the status of active research areas involving stem cells (SCs), cellular therapeutics, and bioengineering as they relate to the human lung. Topics included 1) technological advancements in the in situ analysis of lung tissues, 2) new insights into stem cell signaling and plasticity in lung remodeling and regeneration, 3) the impact of extracellular matrix in stem cell regulation and airway engineering in lung regeneration, 4) differentiating and delivering stem cell therapeutics to the lung, 5) regeneration in response to viral infection, and 6) ethical development of cell-based treatments for lung diseases. This selection of topics represents some of the most dynamic and current research areas in lung biology.

Original languageEnglish (US)
Pages (from-to)L341-L354
JournalAmerican Journal of Physiology - Lung Cellular and Molecular Physiology
Issue number3
StatePublished - Sep 2022

Bibliographical note

Publisher Copyright:
© 2022 American Physiological Society. All rights reserved.


  • Bioengineering
  • Biology
  • COVID-19/therapy
  • Humans
  • Induced Pluripotent Stem Cells
  • Lung
  • Pandemics

PubMed: MeSH publication types

  • Journal Article
  • Review
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.


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