The association of stature and age with measures of second metacarpal cortical bone growth is investigated in a sample of 1586 radiographs taken from Guatemalan Ladino children aged 1-7 years in a setting of endemic mild-to-moderate malnutrition. For given stature, chronological age is positively associated with cortical thickness and cortical area and negatively associated with periosteal and medullary diameter. These different partial correlations are seen as evidence of different kinds of growth. Correlations of cortical bone variables with body size within a chronological age are shown to derive from the overall relationship between age, stature, and measures of cortical bone.
Bibliographical noteFunding Information:
The authors wish to acknowledge the editorial and review procedure for substantially improving the text of this paper. This investigation was supported by the National Institute of Child of Institute Health and Human Development, Bethesda, Maryland (Contract NOI-HD-5-0640), and the Institute of Latin American Studies, University of Texas at Austin, Austin, Texas.