Estatinas y salud ósea

Una minirevisión

Translated title of the contribution: Statins and bone health: A mini review

Research output: Contribution to journalShort survey

Abstract

Statins are a widely prescribed class of medications that inhibit similar pathways as the anti-resorptive bisphosphonate drugs. Statins target the mevalonate pathway by blocking HMG-CoA reductase. Several recent meta-analyses concluded statins are osteo-protective in the general population. Here we present current literature exploring the mechanisms underlying the putative osteoprotective effects of statins. We also review recent clinical studies, ranging from observational cohort studies to randomized clinical trials, testing the effect of statins on bone health in various populations.

Original languageSpanish
Pages (from-to)31-35
Number of pages5
JournalActualizaciones en Osteologia
Volume14
Issue number1
StatePublished - Jan 1 2018

Fingerprint

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Bone and Bones
Health
Hydroxymethylglutaryl CoA Reductases
Mevalonic Acid
Diphosphonates
Population
Observational Studies
Meta-Analysis
Cohort Studies
Randomized Controlled Trials
Pharmaceutical Preparations

Keywords

  • Bone loss
  • Fracture healing
  • Statins

Cite this

Estatinas y salud ósea : Una minirevisión. / Morse, Leslie R.; Coker, Jennifer; Battaglino, Ricardo A.

In: Actualizaciones en Osteologia, Vol. 14, No. 1, 01.01.2018, p. 31-35.

Research output: Contribution to journalShort survey

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