STAT5 and CD4+ T Cell Immunity

Michael A. Farrar, David L. Owen

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations

Abstract

STAT5 plays a critical role in the development and function of many cell types. Here, we review the role of STAT5 in the development of T lymphocytes in the thymus and its subsequent role in the differentiation of distinct CD4+ helper and regulatory T-cell subsets.

Original languageEnglish (US)
Article number32
JournalF1000Research
Volume6
DOIs
StatePublished - 2017

Bibliographical note

Funding Information:
DLO is funded by a National Institutes of Health (NIH) T32 fellowship (T32 AI 007313). MAF is supported by grants from the NIH (R01 AI113138, R01 CA151845, R01 CA154998, and R01 CA185062).

Publisher Copyright:
© 2017 Owen DL and Farrar MA.

Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.

Keywords

  • STAT5
  • T-cell development
  • T-cell function

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