Staphylococcal toxic shock syndrome (TSS) has rarely been reported without rash and desquamation. This study describes a patient who met all criteria for TSS except erythroderma and desquamation. The associated staphylococcal superantigen was enterotoxin B. We demonstrate that erythroderma depends on preexisting T cell hypersensitivity amplified by superantigenicity.
Bibliographical noteFunding Information:
Financial support. US Public Health Service research grants (U54-AI57153 from the Great Lakes Regional Center of Excellence in Biodefense and Emerging Infectious Diseases [of which P.M.S. and D.M.K. are members] and R01-AI064611 from the National Institute of Allergy and Infectious Diseases). Potential conflicts of interest. All authors: no conflicts.