Standardization of pollen allergens of Parthenium hysterophorus and selection of an in-house reference extract

P. Sriramarao, H. Schroder, B. S. Subba Rao, O. Prakash, P. V. Subba Rao

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

A standardized in-house reference extract from the pollen of Parthenium hysterophorus, which is responsible for the high incidence of allergic rhinitis in India, was generated and examined by skin test, radio-allergosorbent test inhibition and isoelectric focusing. Parthenium reference allergen discs and positive reference serum were also generated. These reference reagents could not only be used for the quantitation of Parthenium-specific IgE in the sera of rhinitis patients but also for the evaluation of allergenic activity (relative potency and lot-to-lot variation) of different batches of Parthenium pollen.

Original languageEnglish (US)
Pages (from-to)638-646
Number of pages9
JournalClinical and Experimental Allergy
Volume23
Issue number8
DOIs
StatePublished - Jan 1 1993

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