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Standard fluorescent imaging of live cells is highly genotoxic
Jing Ge
,
David K. Wood
, David M. Weingeist
, Somsak Prasongtanakij
, Panida Navasumrit
, Mathuros Ruchirawat
, Bevin P. Engelward
Biomedical Engineering
Cellular Mechanisms of Cancer
Research output
:
Contribution to journal
›
Article
›
peer-review
55
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Scopus citations
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Keyphrases
Analysis Conditions
11%
Blue Light
22%
Calcein
33%
CometChip
11%
Confounding Effect
11%
Damage Level
11%
DNA Damage
100%
Enhanced Green Fluorescent Protein (eGFP)
11%
Excitation Wavelength
11%
Exposure Time
11%
Fluorescence Imaging
100%
Fluorescence Microscopy
22%
Fluorophore
33%
Fpg Glycosylase
22%
Genotoxic Effect
11%
Green Fluorescent Protein
11%
Green Light
11%
High-throughput Platform
11%
Imaging Condition
11%
Indirect Light
11%
Irradiation Time
11%
Light-induced
22%
Live Mammalian Cell
11%
Living Cells
100%
Nature of Light
11%
Oxidative Damage
11%
Oxidative DNA Damage
22%
Red Fluorophore
11%
Significant Damage
11%
Single-cell Gel Electrophoresis
11%
Standard Filter
11%
Time Lead
11%
Violet Light
22%
Engineering
Blue Light
50%
Damage Level
25%
Data Show
25%
Emitted Light
25%
Exposure Time
25%
Fluorescent Protein
50%
Fluorophore
100%
Gel Electrophoresis
25%
Induced Damage
25%
Lead Time
25%
Live Cell
100%
Oxidative Damage
25%
Selected Wavelength
25%
Pharmacology, Toxicology and Pharmaceutical Science
4',6 Diamidino 2 Phenylindole
33%
Calcein
100%
Enhanced Green Fluorescent Protein
33%
Fluorescence Microscopy
66%
Gel Electrophoresis
33%
Green Fluorescent Protein
33%
Chemistry
Calcein
27%
Comet Assay
9%
DAPI
9%
DNA
100%
Fluorescence Microscopy
18%
Genotoxic
100%
Green Fluorescent Protein
18%
Mammalian Cell
9%
Material Science
Fluorescence Microscopy
100%
Gel Electrophoresis
50%
Oxidative Damage
50%
Food Science
Fluorescence Microscopy
100%