Stakeholder engagement: A key component of integrating genomic information into electronic health records

Andrea Hartzler, Catherine A. McCarty, Luke V. Rasmussen, Marc S. Williams, Murray Brilliant, Erica A. Bowton, Ellen Wright Clayton, William A. Faucett, Kadija Ferryman, Julie R. Field, Stephanie M. Fullerton, Carol R. Horowitz, Barbara A. Koenig, Jennifer B. McCormick, James D. Ralston, Saskia C. Sanderson, Maureen E. Smith, Susan Brown Trinidad

Research output: Contribution to journalReview articlepeer-review

63 Scopus citations


Integrating genomic information into clinical care and the electronic health record can facilitate personalized medicine through genetically guided clinical decision support. Stakeholder involvement is critical to the success of these implementation efforts. Prior work on implementation of clinical information systems provides broad guidance to inform effective engagement strategies. We add to this evidence-based recommendations that are specific to issues at the intersection of genomics and the electronic health record. We describe stakeholder engagement strategies employed by the Electronic Medical Records and Genomics Network, a national consortium of US research institutions funded by the National Human Genome Research Institute to develop, disseminate, and apply approaches that combine genomic and electronic health record data. Through select examples drawn from sites of the Electronic Medical Records and Genomics Network, we illustrate a continuum of engagement strategies to inform genomic integration into commercial and homegrown electronic health records across a range of health-care settings. We frame engagement as activities to consult, involve, and partner with key stakeholder groups throughout specific phases of health information technology implementation. Our aim is to provide insights into engagement strategies to guide genomic integration based on our unique network experiences and lessons learned within the broader context of implementation research in biomedical informatics. On the basis of our collective experience, we describe key stakeholder practices, challenges, and considerations for successful genomic integration to support personalized medicine.

Original languageEnglish (US)
Pages (from-to)792-801
Number of pages10
JournalGenetics in Medicine
Issue number10
StatePublished - Oct 2013


  • electronic health records
  • genomics
  • health information technology
  • personalized medicine
  • stakeholder engagement
  • translational medical research


Dive into the research topics of 'Stakeholder engagement: A key component of integrating genomic information into electronic health records'. Together they form a unique fingerprint.

Cite this