Stability of stereognosis after pediatric repetitive transcranial magnetic stimulation and constraint-induced movement therapy clinical trial

Tonya Rich, Jessica Cassidy, Jeremiah Menk, Ann Van Heest, Linda Krach, James Carey, Bernadette T. Gillick

Research output: Contribution to journalArticlepeer-review

7 Scopus citations


Objective: Poor sensibility affecting stereognosis, the ability to discriminate objects without visual input, can potentiate disuse of the paretic limb following stroke. The purpose of this study was to examine potential change in stereognosis after intervention. Methods: Stereognosis testing in a secondary subgroup of 10 children with hemiparesis and baseline stereognosis deficits (ages 11–16) after a 13-day clinical trial of real or sham repetitive transcranial magnetic stimulation (rTMS) and constraint-induced movement therapy (CIMT) is reported. All children received 10 h of CIMT while wearing a cast full-time. Results: Post-trial, 80% of participants from both intervention groups demonstrated improvement in stereognosis (95% CI: 44.4%–97.5%). Pre-trial to long-term follow-up (range: 21–57 months), 60% retained gains or improved (95% CI: 26.2%–87.8%). Between-group differences were not detected. Discussion: Children demonstrated stereognosis change following intervention. Research on this change and potential minimal clinically important differences are indicated.

Original languageEnglish (US)
Pages (from-to)169-172
Number of pages4
JournalDevelopmental Neurorehabilitation
Issue number3
StatePublished - Apr 3 2017

Bibliographical note

Funding Information:
This study is registered on the United States National Institutes of Health (NIH) (NCT01104064). This study was funded by NIH grant number 1 RC1HD063838-01, 1UL1RR033183-01 from the National Center for Research Resources and by grant number 8 UL1 TR000114-02 from the National Center for Advancing Translational Sciences of the National Institutes of Health to the University of Minnesota Clinical and Translational Science Institute (CTSI). The University of Minnesota Center for Magnetic Resonance Research funding supported the imaging work number P41 EB015894. This research was also supported by the Foundation for Physical Therapy Promotion of Doctoral Studies, the American Academy of Cerebral Palsy and Developmental Medicine Student and OrthoPediatrics Travel Awards University of Minnesota Leadership and Education in Neurodevelopmental Disabilities (LEND) and Minnesota?s Discovery, Research InnoVation Economy (MnDRIVE) fellowships.

Publisher Copyright:
© 2017 Taylor & Francis.

Copyright 2017 Elsevier B.V., All rights reserved.


  • Constraint-induced movement therapy
  • hemiparesis
  • non-invasive brain stimulation
  • pediatrics
  • stroke
  • transcranial magnetic stimulation


Dive into the research topics of 'Stability of stereognosis after pediatric repetitive transcranial magnetic stimulation and constraint-induced movement therapy clinical trial'. Together they form a unique fingerprint.

Cite this