Abstract
Manipulating long DNA molecules has been a topic of longstanding interest at MicroTAS, typically driven by the need for new genomics technologies. This presentation addresses the other side of the coin, examining how nanofluidics enables precise tests of physical models for how semifiexible molecules like DNA behave when they are confined to small spaces. Nanofluidic genomics tools provide especially stringent tests of these physical models and have exposed important gaps in our understanding of DNA-wall electrostatic interactions.
| Original language | English (US) |
|---|---|
| Title of host publication | MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 30-31 |
| Number of pages | 2 |
| ISBN (Electronic) | 9781733419017 |
| State | Published - 2020 |
| Event | 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 - Virtual, Online Duration: Oct 4 2020 → Oct 9 2020 |
Publication series
| Name | MicroTAS 2020 - 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
|---|
Conference
| Conference | 24th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2020 |
|---|---|
| City | Virtual, Online |
| Period | 10/4/20 → 10/9/20 |
Bibliographical note
Publisher Copyright:© 2020 CBMS-0001
Keywords
- DNA
- Genomics
- Nanochannel
- Theory