Abstract
Squamous papillomas of the lung are an uncommon feature of recurrent respiratory papillomatosis (RRP), occurring in fewer than 1% of cases. We describe an 18-year-old male patient with pulmonary papilloma who developed a fatal squamous cell carcinoma of the lung. Both benign papillomas and invasive carcinoma were positive for human papilloma virus subtype 6 and 11. These findings suggest that HPV 6 and 11 are correlated with malignant transformation in the setting of juvenile-onset recurrent respiratory papillomatosis even without tobacco or radiation exposure.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 270-272 |
| Number of pages | 3 |
| Journal | Respiratory Medicine CME |
| Volume | 3 |
| Issue number | 4 |
| DOIs | |
| State | Published - 2010 |
| Externally published | Yes |
Keywords
- HPV 6 and 11
- Recurrent respiratory papillomatosis
- Spontaneous malignant transformation
- Squamous cell carcinoma of the lungs
