Spousal caregiving and incident hypertension

Benjamin D. Capistrant, J. Robin Moon, M. Maria Glymour

Research output: Contribution to journalArticlepeer-review

49 Scopus citations


Background: Caring for one's spouse has been associated with poor health, including risk of cardiovascular disease (CVD) onset and mortality. However, few studies have assessed the risk of incident hypertension associated with spousal caregiving. This paper investigates this association in a large, nationally representative sample of American older adults. Methods: Married, hypertension-free, Health and Retirement Study (HRS) respondents aged 50+ in 2000, (n = 5,708) were followed up to 8 years (1,708 new self-reported hypertension diagnoses). Current caregiving exposure was defined as assisting a spouse with instrumental or basic activities of daily living (IADLs) 14+ h/week; we define providing ≥14 h/week of care at two consecutive biennial surveys as "long-term caregiving." We used inverse probability weighted discrete-time hazard models with time-updated exposure and covariates to estimate effects of current and long-term caregiving on incident hypertension. We tested for effect modification by race, gender, and recipient memory illness. Sensitivity analyses restricted to respondents whose spouses had care needs. Results: After adjusting for demographic, socioeconomic, and health factors, (including risk behaviors, comorbid conditions, and self-rated health), current caregiving significantly predicted hypertension incidence (risk ratio (RR) = 1.36, 95% confidence interval (CI): 1.01, 1.83). For long-term caregivers, there was significant evidence of risk of hypertension onset associated with caregiving (RR = 2.29, 95% CI: 1.17, 4.49). The risk of hypertension onset associated with both current and long-term caregiving did not vary by race, gender, or recipient memory illness diagnosis. Sensitivity analyses supported the primary findings. Conclusions: Providing IADL care to a spouse significantly predicted hypertension onset in a nationally representative sample of US adults.

Original languageEnglish (US)
Pages (from-to)437-443
Number of pages7
JournalAmerican journal of hypertension
Issue number4
StatePublished - Apr 2012
Externally publishedYes

Bibliographical note

Funding Information:
acknowledgment: The authors gratefully acknowledge financial support from the american Heart association grants 09pRE2080078 (B.D.C.) and 10SDG2640243 (M.M.G.), the National institute on aging (aG034385-01) (M.M.G.), and National Heart, Lung, and Blood institute (T32-HL098048-01) (J.R.M.).The HRS (Health and Retirement Study) is sponsored by the National institute on aging (grant number Nia U01aG009740) and is conducted by the University of Michigan.


  • blood pressure
  • caregiver
  • hypertension
  • incidence
  • longitudinal study
  • spouse caregivers
  • spouses


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