TY - CHAP

T1 - Spontaneous curvature effects on spontaneous vesicles

AU - Zasadzinski, J. A.

AU - Jung, H. T.

AU - Coldren, B.

AU - Kaler, E. W.

PY - 2003/11

Y1 - 2003/11

N2 - In mixtures of cetyltrimethylammonium bromide (CTAB) and sodium perfluorooctanoate (FC7) in aqueous solution, novel bilayer cylinders with hemispherical end caps and open, flat discs coexist with spherical unilamellar vesicles, apparently at equilibrium. Such an equilibrium between bilayer cylinders, spheres and discs is only possible for systems with a spontaneous curvature, r0, and a positive Gaussian curvature modulus, κ We have measured the size distributions of the spherical vesicles, cylinders and discs using cryo-electron microscopy; a simple analysis of the size distributions then allows us to independently determine that the mean curvature modulus, κ ≈ 5±1kBT and κ ≈ 2±1kBT. The most probable spherical vesicle radius is 23 nm, giving a spontaneous curvature, r0 =19±1 nm. This is one of the few situations in which r0 , κ , and κ can be determined from the same experiment.

AB - In mixtures of cetyltrimethylammonium bromide (CTAB) and sodium perfluorooctanoate (FC7) in aqueous solution, novel bilayer cylinders with hemispherical end caps and open, flat discs coexist with spherical unilamellar vesicles, apparently at equilibrium. Such an equilibrium between bilayer cylinders, spheres and discs is only possible for systems with a spontaneous curvature, r0, and a positive Gaussian curvature modulus, κ We have measured the size distributions of the spherical vesicles, cylinders and discs using cryo-electron microscopy; a simple analysis of the size distributions then allows us to independently determine that the mean curvature modulus, κ ≈ 5±1kBT and κ ≈ 2±1kBT. The most probable spherical vesicle radius is 23 nm, giving a spontaneous curvature, r0 =19±1 nm. This is one of the few situations in which r0 , κ , and κ can be determined from the same experiment.

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M3 - Chapter

AN - SCOPUS:84880184760

SN - 9781586033828

SP - 432

EP - 442

BT - Self-Assembly

PB - IOS Press

ER -