Abstract
A five-year-old golden retriever was presented with anaemia, thrombocytopenia, anorexia and lethargy. Peripheral blood cytology showed abnormal cells similar to proerythroblasts with multiple nucleoli and strongly basophilic cytoplasm. Bone marrow cytopathology revealed that the blast cells accounted for more than 80% of all nucleated cells (ANC). These blast cells were confirmed as erythroblastic cells by cytochemistry, polymerase chain reaction for genetic clonality assessment of IgH and TCRf, flow cytometry, and transmission electron microscopy. Based on these observations, the dog was diagnosed with acute erythroblastic leukaemia (AML-M6Er). Chemotherapy with cytarabine commenced on day 7 after initial presentation, but the dog died 2 days later. This is the first report of spontaneous AML-M6Er in a dog.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 445-447 |
| Number of pages | 3 |
| Journal | Journal of Small Animal Practice |
| Volume | 52 |
| Issue number | 8 |
| DOIs | |
| State | Published - Aug 2011 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
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