Spin current nano-oscillator (SCNO) as a potential frequency-based, ultra-sensitive magnetic biosensor: A simulation study

Renata Saha, Kai Wu, Diqing Su, Jian Ping Wang

Research output: Contribution to journalArticlepeer-review

Abstract

This work is a micromagnetic simulation-based study on the GHz-frequency ferromagnetic resonances (FMR) for the detection of magnetic nanoparticles (MNPs) using spin current nano-oscillator (SCNO) operating in precession mode. Capture antibody-antigen-detection antibody-MNP complex on the SCNO surface generates magnetic fields that modify the FMR peaks and generate measurable resonance peak shifts. Moreover, our results strongly indicate the position-sensitive behavior of the SCNO biosensor and demonstrate ways to eradicate this effect to facilitate improved bio-sensing. Additionally, a study has been made on how MNPs with different sizes can alter the SCNO device performance. This simulation-based study on the SCNO device shows the feasibility of a frequency-based nano-biosensor with the sensitivity of detecting a single MNP, even in presence of background noise.

Original languageEnglish (US)
Article number375501
JournalNanotechnology
Volume31
Issue number37
DOIs
StatePublished - Sep 11 2020

Keywords

  • frequency-based nanobiosensor
  • magnetic nanoparticles (MNPs)
  • position sensitive behavior
  • single molecule sensitivity
  • spin current nano-oscillator (SCNO)
  • spintronic nanodevice
  • target antibody-antigen-capture antibody-MNP complex

PubMed: MeSH publication types

  • Journal Article

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