Specimen contamination in mycobacteriology laboratory detected by pseudo-outbreak of multidrug-resistant tuberculosis: Analysis by routine epidemiology and confirmation by molecular technique

Rebecca Wurtz, Patricia Demarais, William Trainor, James Mcauley, Frank Kocka, Laura Mosher, Steven Dietrich

Research output: Contribution to journalArticlepeer-review

46 Scopus citations

Abstract

A cluster of multidrug-resistant tuberculosis sputum isolates led to the detection of specimen contamination in a hospital mycobacteriology laboratory. Thirteen specimens were smear negative but culture positive from one specimen only; 12 appeared to be contaminated. Each of these specimens was processed in the same batch as one or more smear- and culture-positive isolates. Molecular analysis confirmed the traditional epidemiologic, laboratory, and clinical methods of evaluating presumed mycobacterial contamination.

Original languageEnglish (US)
Pages (from-to)1017-1019
Number of pages3
JournalJournal of clinical microbiology
Volume34
Issue number4
DOIs
StatePublished - 1996

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