TY - JOUR
T1 - Spatio-temporal source localization and Granger causality in ictal source analysis.
AU - Ding, L.
AU - Worrell, G. A.
AU - Lagerlund, T. D.
AU - He, B.
PY - 2006
Y1 - 2006
N2 - We have proposed a new ictal source analysis approach by combining a spatio-temporal source localization approach, and causal interaction estimation technique. The FINE approach is used to identify neural electrical sources from spatio-temporal scalp-EEGs. The Granger causality estimation uses source waveforms estimated by FINE to characterize the causal interaction between the neural electrical sources in order to distinguish primary sources, which initiate ictal events, from secondary sources, which are caused by propagation. In the present study, we applied the proposed analysis approach to an epilepsy patient with symptomatic MRI lesions. It is found that the primary ictal source is within the visible lesion, which gave the consistent presurgical evaluation as MRI for this patient.
AB - We have proposed a new ictal source analysis approach by combining a spatio-temporal source localization approach, and causal interaction estimation technique. The FINE approach is used to identify neural electrical sources from spatio-temporal scalp-EEGs. The Granger causality estimation uses source waveforms estimated by FINE to characterize the causal interaction between the neural electrical sources in order to distinguish primary sources, which initiate ictal events, from secondary sources, which are caused by propagation. In the present study, we applied the proposed analysis approach to an epilepsy patient with symptomatic MRI lesions. It is found that the primary ictal source is within the visible lesion, which gave the consistent presurgical evaluation as MRI for this patient.
UR - http://www.scopus.com/inward/record.url?scp=84903876858&partnerID=8YFLogxK
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U2 - 10.1109/IEMBS.2006.259393
DO - 10.1109/IEMBS.2006.259393
M3 - Article
C2 - 17947049
AN - SCOPUS:34047095437
SN - 1557-170X
SP - 3670
EP - 3671
JO - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
JF - Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference
T2 - 28th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS'06
Y2 - 30 August 2006 through 3 September 2006
ER -