Somatic Mutational Landscape of Splicing Factor Genes and Their Functional Consequences across 33 Cancer Types

Keyphrases

• Functional Consequences 100%
• Cancer Types 100%
• Mutational Landscape 100%
• Splicing Factor Genes 100%
• In Cancer 50%
• Tumor Subtype 50%
• RNA Splicing 50%
• Cancer Genome Atlas 50%
• Hotspot mutation 50%
• Hematological Malignancies 25%
• Loss Function 25%
• Tumor Suppressor 25%
• Sequence Data 25%
• Oncogene 25%
• Non-cell Autonomous 25%
• Tumorigenesis 25%
• RNA-seq Analysis 25%
• Whole Exome Sequencing 25%
• Deregulation 25%
• Immune Infiltration 25%
• Splicing Event 25%
• Somatic Alterations 25%
• Gene Pathway 25%
• Underrepresentation 25%
• Mutually Exclusive 25%
• Mutation Pattern 25%
• Uncommon mutation 25%
• Common Genes 25%
• Silent mutation 25%
• Mutation Profiling 25%
• Driver mutations 25%
• Pathway Profile 25%
• Autonomous Pathway 25%
• Splicing Process 25%
• Splicing Factor mutations 25%

Biochemistry, Genetics and Molecular Biology

• Splicing Factor 100%
• RNA Splicing 40%
• Oncogene 20%
• Tumor Suppressor Protein 20%
• Exome Sequencing 20%
• Immunity 20%
• RNA Sequence 20%
• Silent Mutation 20%
• Carcinogenesis 20%