Solid-phase synthesis of N-substituted 3,4-dihydroquinazolinone derivatives

Zhang Liu; Lili Ou; Marc A. Giulianotti; Richard A. Houghten

doi:10.1016/j.tetlet.2011.03.034

Solid-phase synthesis of N-substituted 3,4-dihydroquinazolinone derivatives

Zhang Liu, Lili Ou, Marc A. Giulianotti, Richard A. Houghten

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

An efficient solid-phase synthetic approach for the synthesis of N-substituted 3, 4-dihydroquinazolinone derivatives has been developed. Four different 2-nitrobenzoic acids and three different 2-phenylacetyl chlorides were employed in the synthesis of this library. After purification, all products were obtained in good yields.

Original language	English (US)
Pages (from-to)	2627-2628
Number of pages	2
Journal	Tetrahedron Letters
Volume	52
Issue number	21
DOIs	https://doi.org/10.1016/j.tetlet.2011.03.034
State	Published - May 25 2011
Externally published	Yes

Bibliographical note

Funding Information:
This work was supported by the State of Florida, Executive Officer of the Governor’s Office of Tourism, Trade, and Economic Development .

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10.1016/j.tetlet.2011.03.034

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abstract = "An efficient solid-phase synthetic approach for the synthesis of N-substituted 3, 4-dihydroquinazolinone derivatives has been developed. Four different 2-nitrobenzoic acids and three different 2-phenylacetyl chlorides were employed in the synthesis of this library. After purification, all products were obtained in good yields.",

author = "Zhang Liu and Lili Ou and Giulianotti, {Marc A.} and Houghten, {Richard A.}",

note = "Funding Information: This work was supported by the State of Florida, Executive Officer of the Governor{\textquoteright}s Office of Tourism, Trade, and Economic Development . ",

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T1 - Solid-phase synthesis of N-substituted 3,4-dihydroquinazolinone derivatives

AU - Liu, Zhang

AU - Ou, Lili

AU - Giulianotti, Marc A.

AU - Houghten, Richard A.

N1 - Funding Information: This work was supported by the State of Florida, Executive Officer of the Governor’s Office of Tourism, Trade, and Economic Development .

PY - 2011/5/25

Y1 - 2011/5/25

N2 - An efficient solid-phase synthetic approach for the synthesis of N-substituted 3, 4-dihydroquinazolinone derivatives has been developed. Four different 2-nitrobenzoic acids and three different 2-phenylacetyl chlorides were employed in the synthesis of this library. After purification, all products were obtained in good yields.

AB - An efficient solid-phase synthetic approach for the synthesis of N-substituted 3, 4-dihydroquinazolinone derivatives has been developed. Four different 2-nitrobenzoic acids and three different 2-phenylacetyl chlorides were employed in the synthesis of this library. After purification, all products were obtained in good yields.

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ER -

Solid-phase synthesis of N-substituted 3,4-dihydroquinazolinone derivatives

Abstract

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