Solid-phase synthesis of 2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine derivatives

Zhang Liu; Wenteng Chen; Marc A. Giulianotti; Richard A. Houghten

doi:10.1016/j.tetlet.2011.05.138

Solid-phase synthesis of 2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine derivatives

Zhang Liu
, Wenteng Chen
, Marc A. Giulianotti
, Richard A. Houghten

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

We have developed an efficient solid-phase synthetic approach for the synthesis of 2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine derivatives. The methodology is of value for high throughput synthesis of these potentially bioactive molecules.

Original language	English (US)
Pages (from-to)	4112-4113
Number of pages	2
Journal	Tetrahedron Letters
Volume	52
Issue number	32
DOIs	https://doi.org/10.1016/j.tetlet.2011.05.138
State	Published - Aug 10 2011
Externally published	Yes

Bibliographical note

Funding Information:
This work was supported by the State of Florida, Executive Officer of the Governor’s Office of Tourism, Trade and Economic Development.

Keywords

Diazepine
Heterocycle
Solid-phase

Publisher link

10.1016/j.tetlet.2011.05.138

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title = "Solid-phase synthesis of 2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine derivatives",

abstract = "We have developed an efficient solid-phase synthetic approach for the synthesis of 2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine derivatives. The methodology is of value for high throughput synthesis of these potentially bioactive molecules.",

keywords = "Diazepine, Heterocycle, Solid-phase",

author = "Zhang Liu and Wenteng Chen and Giulianotti, \{Marc A.\} and Houghten, \{Richard A.\}",

note = "Funding Information: This work was supported by the State of Florida, Executive Officer of the Governor{\textquoteright}s Office of Tourism, Trade and Economic Development. ",

year = "2011",

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day = "10",

doi = "10.1016/j.tetlet.2011.05.138",

language = "English (US)",

volume = "52",

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journal = "Tetrahedron Letters",

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T1 - Solid-phase synthesis of 2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine derivatives

AU - Liu, Zhang

AU - Chen, Wenteng

AU - Giulianotti, Marc A.

AU - Houghten, Richard A.

N1 - Funding Information: This work was supported by the State of Florida, Executive Officer of the Governor’s Office of Tourism, Trade and Economic Development.

PY - 2011/8/10

Y1 - 2011/8/10

N2 - We have developed an efficient solid-phase synthetic approach for the synthesis of 2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine derivatives. The methodology is of value for high throughput synthesis of these potentially bioactive molecules.

AB - We have developed an efficient solid-phase synthetic approach for the synthesis of 2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine derivatives. The methodology is of value for high throughput synthesis of these potentially bioactive molecules.

KW - Diazepine

KW - Heterocycle

KW - Solid-phase

UR - https://www.scopus.com/pages/publications/79960391789

UR - https://www.scopus.com/pages/publications/79960391789#tab=citedBy

U2 - 10.1016/j.tetlet.2011.05.138

DO - 10.1016/j.tetlet.2011.05.138

M3 - Article

AN - SCOPUS:79960391789

SN - 0040-4039

VL - 52

SP - 4112

EP - 4113

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 32

ER -

Solid-phase synthesis of 2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine derivatives

Abstract

Bibliographical note

Keywords

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