Solid-phase synthesis of 2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine derivatives

Zhang Liu, Wenteng Chen, Marc A. Giulianotti, Richard A. Houghten

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

We have developed an efficient solid-phase synthetic approach for the synthesis of 2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine derivatives. The methodology is of value for high throughput synthesis of these potentially bioactive molecules.

Original languageEnglish (US)
Pages (from-to)4112-4113
Number of pages2
JournalTetrahedron Letters
Volume52
Issue number32
DOIs
StatePublished - Aug 10 2011
Externally publishedYes

Bibliographical note

Funding Information:
This work was supported by the State of Florida, Executive Officer of the Governor’s Office of Tourism, Trade and Economic Development.

Keywords

  • Diazepine
  • Heterocycle
  • Solid-phase

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