Solid-phase syntheses of furopyridine and furoquinoline systems

Pablo Cironi, Judit Tulla-Puche, George Barany, Fernando Albericio, Mercedes Álvarez

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

Syntheses of 2-substituted furo[3,2-b]pyridines and furo[3,2-h]quinolines have been achieved for the first time in the solid-phase mode. The central enabling steps involved concomitant deprotection/cyclization promoted by the mild base K2CO3. Reactions were monitored "in situ" in real time by a variety of spectroscopic techniques, which allowed full and accurate control of progress in these syntheses.

Original languageEnglish (US)
Pages (from-to)1405-1408
Number of pages4
JournalOrganic Letters
Volume6
Issue number9
DOIs
StatePublished - Apr 29 2004

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