Phosphorane ylides and phosphonate anions react smoothly with resin-bound aldehydes and ketones to provide alkenes in good yields and purities (assessed after cleavage of acid-labile PAL anchor to support). The reactions of aldehydes give excellent stereoselectivities. Effective conditions have been developed for carrying out these transformations.
|Original language||English (US)|
|Number of pages||6|
|Journal||Collection of Czechoslovak Chemical Communications|
|State||Published - Dec 1996|
- Combinatorial chemistry
- Solid-phase synthesis
- Wittig reaction