Soft mold-dry etch: A novel hydrogel patterning technique for biomedical applications

Ming Lei, Yuandong Gu, Antonio Baldi, Ronald A. Siegel, Babak Ziaie

Research output: Contribution to journalConference article

3 Scopus citations

Abstract

This paper introduces a novel patterning technique for environmentally sensitive hydrogels using a combination of soft mold and dry etch. This method alleviates the need for photoinitiators used in conventional approaches and is applicable to a broad range of hydrogels. This technique is also compatible with the traditional microfabrication methods thus allowing the integration of hydrogels with microelectronics and MEMS microstructures. Hydrogels of different shapes and sizes were patterned in a batch scale (wafer-level) with resolutions of up to 2.5μm. The patterned pH-sensitive hydrogels with micron-sized dimensions were able to respond within seconds. Deposited aluminum thin films on top of hydrogel microstructures was used to fabricate environmentally sensitive free standing micromirrors with a vertical displacement sensitivity of 7μm/pH at pH 5.0. These structures open the possibility of fabricating on-chip photonic-based hydrogel microsensors.

Original languageEnglish (US)
Pages (from-to)1983-1986
Number of pages4
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume26 III
StatePublished - Dec 1 2004
EventConference Proceedings - 26th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2004 - San Francisco, CA, United States
Duration: Sep 1 2004Sep 5 2004

Keywords

  • BioMEMS
  • Dry patterning
  • Hydrogel
  • Microfluidic
  • Soft lithography

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