Sodium binding by rat brain lipoprotein

K. Ahmed; J. D. Judah

doi:10.1016/S0926-6585(96)90008-4

Sodium binding by rat brain lipoprotein

K. Ahmed
, J. D. Judah

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

1. 1. Rat brain lipoprotein can bind Na⁺. 2. 2. ATP increases the binding of Na⁺ but the effect is due to removal of Mg²⁺ from binding sites. 3. 3. EDTA is even more effective than ATP in increasing Na⁺ binding by the protein. 4. 4. Na⁺ binding by protein is not necessarily related to the cation-stimulated ATPase activity of the protein. 5. 5. Other ions such as K⁺, Li⁺, Mg²⁺ bind as effectively to the protein as Na²⁺. 6. 6. The present methods are inadequate to determine if Na⁺ is bound to phosphorylated intermediate in cation-activated ATPase systems.

Original language	English (US)
Pages (from-to)	58-62
Number of pages	5
Journal	BBA - Biophysics Including Photosynthesis
Volume	112
Issue number	1
DOIs	https://doi.org/10.1016/S0926-6585(96)90008-4
State	Published - Jan 4 1966

Bibliographical note

Funding Information:
This work was supportebdy Grant NumberA MO7226f romthe NationalI nsti-tuteso f Health,t he Life InsuranceM edicalR esearchF und, the Otho S. A. Sprague MemorialI nstitutea ndthe Burroughs-WellcomFuen d. Mrs. J. AUSTIN gaves killedt echnicaal ssistancteh roughoutth e work.

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title = "Sodium binding by rat brain lipoprotein",

abstract = "1. 1. Rat brain lipoprotein can bind Na+. 2. 2. ATP increases the binding of Na+ but the effect is due to removal of Mg2+ from binding sites. 3. 3. EDTA is even more effective than ATP in increasing Na+ binding by the protein. 4. 4. Na+ binding by protein is not necessarily related to the cation-stimulated ATPase activity of the protein. 5. 5. Other ions such as K+, Li+, Mg2+ bind as effectively to the protein as Na2+. 6. 6. The present methods are inadequate to determine if Na+ is bound to phosphorylated intermediate in cation-activated ATPase systems.",

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AU - Judah, J. D.

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N2 - 1. 1. Rat brain lipoprotein can bind Na+. 2. 2. ATP increases the binding of Na+ but the effect is due to removal of Mg2+ from binding sites. 3. 3. EDTA is even more effective than ATP in increasing Na+ binding by the protein. 4. 4. Na+ binding by protein is not necessarily related to the cation-stimulated ATPase activity of the protein. 5. 5. Other ions such as K+, Li+, Mg2+ bind as effectively to the protein as Na2+. 6. 6. The present methods are inadequate to determine if Na+ is bound to phosphorylated intermediate in cation-activated ATPase systems.

AB - 1. 1. Rat brain lipoprotein can bind Na+. 2. 2. ATP increases the binding of Na+ but the effect is due to removal of Mg2+ from binding sites. 3. 3. EDTA is even more effective than ATP in increasing Na+ binding by the protein. 4. 4. Na+ binding by protein is not necessarily related to the cation-stimulated ATPase activity of the protein. 5. 5. Other ions such as K+, Li+, Mg2+ bind as effectively to the protein as Na2+. 6. 6. The present methods are inadequate to determine if Na+ is bound to phosphorylated intermediate in cation-activated ATPase systems.

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JF - BBA - Biophysics Including Photosynthesis

IS - 1

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Sodium binding by rat brain lipoprotein

Abstract

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