Social network, social support, and risk of incident stroke

Atherosclerosis risk in communities study

Mako Nagayoshi, Susan A. Everson-Rose, Hiroyasu Iso, Thomas H. Mosley, Kathryn M. Rose, Pamela L. Lutsey

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

BACKGROUND AND PURPOSE -: Having a small social network and lack of social support have been associated with incident coronary heart disease; however, epidemiological evidence for incident stroke is limited. We assessed the longitudinal association of a small social network and lack of social support with risk of incident stroke and evaluated whether the association was partly mediated by vital exhaustion and inflammation. METHODS -: The Atherosclerosis Risk in Communities study measured social network and social support in 13 686 men and women (mean, 57 years; 56% women; 24% black; 76% white) without a history of stroke. Social network was assessed by the 10-item Lubben Social Network Scale and social support by a 16-item Interpersonal Support Evaluation List-Short Form. RESULTS -: During a median follow-up of 18.6 years, 905 incident strokes occurred. Relative to participants with a large social network, those with a small social network had a higher risk of stroke (hazard ratio [95% confidence interval], 1.44 [1.02-2.04]) after adjustment for demographics, socioeconomic variables, marital status, behavioral risk factors, and major stroke risk factors. Vital exhaustion, but not inflammation, partly mediated the association between a small social network and incident stroke. Social support was unrelated to incident stroke. CONCLUSIONS -: In this sample of US community-dwelling men and women, having a small social network was associated with excess risk of incident stroke. As with other cardiovascular conditions, having a small social network may be associated with a modestly increased risk of incident stroke.

Original languageEnglish (US)
Pages (from-to)2868-2873
Number of pages6
JournalStroke
Volume45
Issue number10
DOIs
StatePublished - Jan 1 2014

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Social Support
Atherosclerosis
Stroke
Inflammation
Independent Living
Marital Status
Coronary Disease
Demography

Keywords

  • epidemiology
  • inflammation
  • social support
  • stroke

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Social network, social support, and risk of incident stroke : Atherosclerosis risk in communities study. / Nagayoshi, Mako; Everson-Rose, Susan A.; Iso, Hiroyasu; Mosley, Thomas H.; Rose, Kathryn M.; Lutsey, Pamela L.

In: Stroke, Vol. 45, No. 10, 01.01.2014, p. 2868-2873.

Research output: Contribution to journalArticle

Nagayoshi, Mako ; Everson-Rose, Susan A. ; Iso, Hiroyasu ; Mosley, Thomas H. ; Rose, Kathryn M. ; Lutsey, Pamela L. / Social network, social support, and risk of incident stroke : Atherosclerosis risk in communities study. In: Stroke. 2014 ; Vol. 45, No. 10. pp. 2868-2873.
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