TY - JOUR
T1 - Smartphone Analytics
T2 - Mobilizing the Lab into the Cloud for Omic-Scale Analyses
AU - Montenegro-Burke, J. Rafael
AU - Phommavongsay, Thiery
AU - Aisporna, Aries E.
AU - Huan, Tao
AU - Rinehart, Duane
AU - Forsberg, Erica
AU - Poole, Farris L.
AU - Thorgersen, Michael P.
AU - Adams, Michael W.W.
AU - Krantz, Gregory
AU - Fields, Matthew W.
AU - Northen, Trent R.
AU - Robbins, Paul D.
AU - Niedernhofer, Laura J.
AU - Lairson, Luke
AU - Benton, H. Paul
AU - Siuzdak, Gary
N1 - Publisher Copyright:
© 2016 American Chemical Society.
PY - 2016/10/4
Y1 - 2016/10/4
N2 - Active data screening is an integral part of many scientific activities, and mobile technologies have greatly facilitated this process by minimizing the reliance on large hardware instrumentation. In order to meet with the increasingly growing field of metabolomics and heavy workload of data processing, we designed the first remote metabolomic data screening platform for mobile devices. Two mobile applications (apps), XCMS Mobile and METLIN Mobile, facilitate access to XCMS and METLIN, which are the most important components in the computer-based XCMS Online platforms. These mobile apps allow for the visualization and analysis of metabolic data throughout the entire analytical process. Specifically, XCMS Mobile and METLIN Mobile provide the capabilities for remote monitoring of data processing, real time notifications for the data processing, visualization and interactive analysis of processed data (e.g., cloud plots, principle component analysis, box-plots, extracted ion chromatograms, and hierarchical cluster analysis), and database searching for metabolite identification. These apps, available on Apple iOS and Google Android operating systems, allow for the migration of metabolomic research onto mobile devices for better accessibility beyond direct instrument operation. The utility of XCMS Mobile and METLIN Mobile functionalities was developed and is demonstrated here through the metabolomic LC-MS analyses of stem cells, colon cancer, aging, and bacterial metabolism.
AB - Active data screening is an integral part of many scientific activities, and mobile technologies have greatly facilitated this process by minimizing the reliance on large hardware instrumentation. In order to meet with the increasingly growing field of metabolomics and heavy workload of data processing, we designed the first remote metabolomic data screening platform for mobile devices. Two mobile applications (apps), XCMS Mobile and METLIN Mobile, facilitate access to XCMS and METLIN, which are the most important components in the computer-based XCMS Online platforms. These mobile apps allow for the visualization and analysis of metabolic data throughout the entire analytical process. Specifically, XCMS Mobile and METLIN Mobile provide the capabilities for remote monitoring of data processing, real time notifications for the data processing, visualization and interactive analysis of processed data (e.g., cloud plots, principle component analysis, box-plots, extracted ion chromatograms, and hierarchical cluster analysis), and database searching for metabolite identification. These apps, available on Apple iOS and Google Android operating systems, allow for the migration of metabolomic research onto mobile devices for better accessibility beyond direct instrument operation. The utility of XCMS Mobile and METLIN Mobile functionalities was developed and is demonstrated here through the metabolomic LC-MS analyses of stem cells, colon cancer, aging, and bacterial metabolism.
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U2 - 10.1021/acs.analchem.6b02676
DO - 10.1021/acs.analchem.6b02676
M3 - Article
C2 - 27560777
AN - SCOPUS:84989900449
SN - 0003-2700
VL - 88
SP - 9753
EP - 9758
JO - Analytical Chemistry
JF - Analytical Chemistry
IS - 19
ER -
