Small-molecule nociceptin receptor agonist ameliorates mast cell activation and pain in sickle mice

Keyphrases

• Small Molecules 100%
• Mast Cell Activation 100%
• Receptor Agonist 100%
• Nociceptin 100%
• Nociceptin Receptor 100%
• Opioid Antagonist 60%
• Opioid Receptors 40%
• Antinociceptive 40%
• Sickle Cell Anemia 40%
• Hyperalgesia 20%
• Morphine 20%
• Inflammatory Cytokines 20%
• Addiction 20%
• μ-opioid Receptor 20%
• Ligand-receptor Binding 20%
• High Affinity 20%
• Analgesic 20%
• Analgesic Efficacy 20%
• Neuropeptides 20%
• Pain Treatment 20%
• Mechanical Tissues 20%
• Naloxone 20%
• Hypoxia-reoxygenation 20%
• Non-selective 20%
• Promising Drug 20%
• HbSS 20%
• Deep Tissue 20%
• Mu-opioid Receptor Antagonist 20%
• Serum Amyloid A Protein 20%
• Acute Pain Model 20%
• SB-612111 20%
• Chronic Pain Model 20%
• Days of Treatment 20%
• Inflammation Cells 20%

Medicine and Dentistry

• Cell Activation 100%
• Nociceptin Receptor Agonist 100%
• Mast Cell 100%
• Nociceptin 100%
• Sickle-Cell Disease 40%
• Opiate Agonist 40%
• Opioid Receptor 40%
• Pain 20%
• Addictive Behavior 20%
• Hypoxia 20%
• Hyperpathia 20%
• Anodyne 20%
• Chronic Pain 20%
• Opiate Antagonist 20%
• Side Effect 20%
• Mu Opiate Receptor Antagonist 20%
• Amyloid Protein 20%
• Treatment of Pain 20%
• Inflammatory Cytokine 20%
• Analgesic Efficacy 20%
• Neuropeptide 20%
• Morphine 20%
• μ-Opioid Receptor 20%
• Naloxone 20%