Slow persistent infection caused by visna virus: Role of host restriction

Ashley T. Haase; Linda Stowring; Opendra Narayan; Dianne Griffin; Donald Price

doi:10.1126/science.188133

Slow persistent infection caused by visna virus: Role of host restriction

Ashley T. Haase
, Linda Stowring
, Opendra Narayan
, Dianne Griffin
, Donald Price

Microbiology

Research output: Contribution to journal › Article › peer-review

107 Scopus citations

Abstract

Proviral DNA has been demonstrated by in situ hybridization in foci of cells of a lamb infected with the RNA slow virus visna. A few of these cells also contain the major virion structural antigen p30. This restriction in virus gene expression in the infected animal provides a mechanism for persistence of virus in this chronic infection.

Original language	English (US)
Pages (from-to)	175-177
Number of pages	3
Journal	Science
Volume	195
Issue number	4274
DOIs	https://doi.org/10.1126/science.188133
State	Published - 1977

Publisher link

10.1126/science.188133

Find It

Find It at U of M Libraries

Cite this

@article{0204853486bb4914a30ffe9effa7eb10,

title = "Slow persistent infection caused by visna virus: Role of host restriction",

abstract = "Proviral DNA has been demonstrated by in situ hybridization in foci of cells of a lamb infected with the RNA slow virus visna. A few of these cells also contain the major virion structural antigen p30. This restriction in virus gene expression in the infected animal provides a mechanism for persistence of virus in this chronic infection.",

author = "Haase, \{Ashley T.\} and Linda Stowring and Opendra Narayan and Dianne Griffin and Donald Price",

year = "1977",

doi = "10.1126/science.188133",

language = "English (US)",

volume = "195",

pages = "175--177",

journal = "Science",

issn = "0036-8075",

publisher = "American Association for the Advancement of Science",

number = "4274",

}

TY - JOUR

T1 - Slow persistent infection caused by visna virus

T2 - Role of host restriction

AU - Haase, Ashley T.

AU - Stowring, Linda

AU - Narayan, Opendra

AU - Griffin, Dianne

AU - Price, Donald

PY - 1977

Y1 - 1977

N2 - Proviral DNA has been demonstrated by in situ hybridization in foci of cells of a lamb infected with the RNA slow virus visna. A few of these cells also contain the major virion structural antigen p30. This restriction in virus gene expression in the infected animal provides a mechanism for persistence of virus in this chronic infection.

AB - Proviral DNA has been demonstrated by in situ hybridization in foci of cells of a lamb infected with the RNA slow virus visna. A few of these cells also contain the major virion structural antigen p30. This restriction in virus gene expression in the infected animal provides a mechanism for persistence of virus in this chronic infection.

UR - https://www.scopus.com/pages/publications/0017577407

UR - https://www.scopus.com/pages/publications/0017577407#tab=citedBy

U2 - 10.1126/science.188133

DO - 10.1126/science.188133

M3 - Article

C2 - 188133

AN - SCOPUS:0017577407

SN - 0036-8075

VL - 195

SP - 175

EP - 177

JO - Science

JF - Science

IS - 4274

ER -

Slow persistent infection caused by visna virus: Role of host restriction

Abstract

Publisher link

Find It

Other files and links

Fingerprint

Cite this