TY - JOUR
T1 - Skin Malignancies
T2 - Imaging Review with Radiologic-Histopathologic Correlation
AU - Pathak, Priya
AU - Wondimu, Bitania
AU - Jalilianhasanpour, Rozita
AU - Pooyan, Atefe
AU - Matesan, Manuela C.
AU - Mansoori, Bahar
N1 - Publisher Copyright:
© RSNA, 2023.
PY - 2023/12
Y1 - 2023/12
N2 - Skin malignancies are commonly encountered as primary or incidental findings. Neoplasms that affect the skin include primary (basal cell carcinoma, squamous cell carcinoma, melanoma, and Merkel cell carcinoma) and secondary (mesenchymal neoplasms, lymphoma, and metastases) tumors. Imaging provides valuable anatomic information (tumor size, depth of involvement, presence of distant metastasis, and data for guiding biopsy) and functional information (metabolic activity and sentinel node mapping data). This information, in addition to biopsy results, improves the histopathologic characterization of tumors and treatment planning. Various histopathologic types of the same entity exhibit different biologic behavior and have different imaging features. Familiarity with the multimodality imaging features, histopathologic characteristics, and various modes of dissemination (direct invasion; perineural, lymphatic, and hematogenous spread) of the most common skin malignancies helps radiologists narrow the differential diagnosis in clinical practice.
AB - Skin malignancies are commonly encountered as primary or incidental findings. Neoplasms that affect the skin include primary (basal cell carcinoma, squamous cell carcinoma, melanoma, and Merkel cell carcinoma) and secondary (mesenchymal neoplasms, lymphoma, and metastases) tumors. Imaging provides valuable anatomic information (tumor size, depth of involvement, presence of distant metastasis, and data for guiding biopsy) and functional information (metabolic activity and sentinel node mapping data). This information, in addition to biopsy results, improves the histopathologic characterization of tumors and treatment planning. Various histopathologic types of the same entity exhibit different biologic behavior and have different imaging features. Familiarity with the multimodality imaging features, histopathologic characteristics, and various modes of dissemination (direct invasion; perineural, lymphatic, and hematogenous spread) of the most common skin malignancies helps radiologists narrow the differential diagnosis in clinical practice.
UR - http://www.scopus.com/inward/record.url?scp=85178504445&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85178504445&partnerID=8YFLogxK
U2 - 10.1148/rg.230093
DO - 10.1148/rg.230093
M3 - Article
C2 - 38032822
AN - SCOPUS:85178504445
SN - 0271-5333
VL - 43
JO - Radiographics
JF - Radiographics
IS - 12
M1 - e230093
ER -