Six Long-Standing Questions about Antibiotic Prophylaxis in Surgery

Massimo Sartelli, Marja A. Boermeester, Miguel Cainzos, Federico Coccolini, Stijn W. de Jonge, Kemal Rasa, E. Patchen Dellinger, Deborah A. McNamara, Donald E. Fry, Yunfeng Cui, Samir Delibegovic, Zaza Demetrashvili, Belinda De Simone, George Gkiokas, Timothy C. Hardcastle, Kamal M.F. Itani, Arda Isik, Francesco Maria Labricciosa, Varut Lohsiriwat, Sanjay MarwahTadeja Pintar, Jennifer Rickard, Vishal G. Shelat, Fausto Catena, Philip S. Barie

Research output: Contribution to journalReview articlepeer-review

9 Scopus citations

Abstract

Surgical site infections (SSIs) are the most common adverse event occurring in surgical patients. Optimal prevention of SSIs requires the bundled integration of a variety of measures before, during, and after surgery. Surgical antibiotic prophylaxis (SAP) is an effective measure for preventing SSIs. It aims to counteract the inevitable introduction of bacteria that colonize skin or mucosa into the surgical site during the intervention. This document aims to guide surgeons in appropriate administration of SAP by addressing six key questions. The expert panel identifies a list of principles in response to these questions that every surgeon around the world should always respect in administering SAP.

Original languageEnglish (US)
Article number908
JournalAntibiotics
Volume12
Issue number5
DOIs
StatePublished - May 2023

Bibliographical note

Publisher Copyright:
© 2023 by the authors.

Keywords

  • healthcare-associated infections
  • surgical antibiotic prophylaxis
  • surgical site infections

PubMed: MeSH publication types

  • Journal Article
  • Review

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