Single nucleotide polymorphisms in the IS900 sequence of Mycobacterium avium subsp. paratuberculosis are strain type specific

Elena Castellanos, Alicia Aranaz, Lucia De Juan, Julio Álvarez, Sabrina Rodríguez, Beatriz Romero, Javier Bezos, Karen Stevenson, Ana Mateos, Lucas Domínguez

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

Insertion sequence IS900 is used as a target for the identification of Mycobacterium avium subsp. paratuberculosis. Previous reports have revealed single nucleotide polymorphisms within IS900. This study, which analyzed the IS900 sequences of a panel of isolates representing M. avium subsp. paratuberculosis strain types I, II, and III, revealed conserved type-specific polymorphisms that could be utilized as a tool for diagnostic and epidemiological purposes.

Original languageEnglish (US)
Pages (from-to)2260-2264
Number of pages5
JournalJournal of clinical microbiology
Volume47
Issue number7
DOIs
StatePublished - Jul 2009

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