Single nucleotide polymorphisms in the IS900 sequence of Mycobacterium avium subsp. paratuberculosis are strain type specific

Elena Castellanos; Alicia Aranaz; Lucia De Juan; Julio Álvarez; Sabrina Rodríguez; Beatriz Romero; Javier Bezos; Karen Stevenson; Ana Mateos; Lucas Domínguez

doi:10.1128/JCM.00544-09

Single nucleotide polymorphisms in the IS900 sequence of Mycobacterium avium subsp. paratuberculosis are strain type specific

Elena Castellanos, Alicia Aranaz, Lucia De Juan, Julio Álvarez, Sabrina Rodríguez, Beatriz Romero, Javier Bezos, Karen Stevenson, Ana Mateos, Lucas Domínguez

Research output: Contribution to journal › Article › peer-review

31 Scopus citations

Abstract

Insertion sequence IS900 is used as a target for the identification of Mycobacterium avium subsp. paratuberculosis. Previous reports have revealed single nucleotide polymorphisms within IS900. This study, which analyzed the IS900 sequences of a panel of isolates representing M. avium subsp. paratuberculosis strain types I, II, and III, revealed conserved type-specific polymorphisms that could be utilized as a tool for diagnostic and epidemiological purposes.

Original language	English (US)
Pages (from-to)	2260-2264
Number of pages	5
Journal	Journal of clinical microbiology
Volume	47
Issue number	7
DOIs	https://doi.org/10.1128/JCM.00544-09
State	Published - Jul 2009
Externally published	Yes

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10.1128/JCM.00544-09

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title = "Single nucleotide polymorphisms in the IS900 sequence of Mycobacterium avium subsp. paratuberculosis are strain type specific",

abstract = "Insertion sequence IS900 is used as a target for the identification of Mycobacterium avium subsp. paratuberculosis. Previous reports have revealed single nucleotide polymorphisms within IS900. This study, which analyzed the IS900 sequences of a panel of isolates representing M. avium subsp. paratuberculosis strain types I, II, and III, revealed conserved type-specific polymorphisms that could be utilized as a tool for diagnostic and epidemiological purposes.",

author = "Elena Castellanos and Alicia Aranaz and {De Juan}, Lucia and Julio {\'A}lvarez and Sabrina Rodr{\'i}guez and Beatriz Romero and Javier Bezos and Karen Stevenson and Ana Mateos and Lucas Dom{\'i}nguez",

year = "2009",

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doi = "10.1128/JCM.00544-09",

language = "English (US)",

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T1 - Single nucleotide polymorphisms in the IS900 sequence of Mycobacterium avium subsp. paratuberculosis are strain type specific

AU - Castellanos, Elena

AU - Aranaz, Alicia

AU - De Juan, Lucia

AU - Álvarez, Julio

AU - Rodríguez, Sabrina

AU - Romero, Beatriz

AU - Bezos, Javier

AU - Stevenson, Karen

AU - Mateos, Ana

AU - Domínguez, Lucas

PY - 2009/7

Y1 - 2009/7

N2 - Insertion sequence IS900 is used as a target for the identification of Mycobacterium avium subsp. paratuberculosis. Previous reports have revealed single nucleotide polymorphisms within IS900. This study, which analyzed the IS900 sequences of a panel of isolates representing M. avium subsp. paratuberculosis strain types I, II, and III, revealed conserved type-specific polymorphisms that could be utilized as a tool for diagnostic and epidemiological purposes.

AB - Insertion sequence IS900 is used as a target for the identification of Mycobacterium avium subsp. paratuberculosis. Previous reports have revealed single nucleotide polymorphisms within IS900. This study, which analyzed the IS900 sequences of a panel of isolates representing M. avium subsp. paratuberculosis strain types I, II, and III, revealed conserved type-specific polymorphisms that could be utilized as a tool for diagnostic and epidemiological purposes.

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Single nucleotide polymorphisms in the IS900 sequence of Mycobacterium avium subsp. paratuberculosis are strain type specific

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