Single night studies in obstructive sleep apnea

Conrad Iber, C. O'Brien, J. Schluter, S. Davies, J. Leatherman, M. Mahowald

Research output: Contribution to journalArticlepeer-review

55 Scopus citations


The role of single night studies and the determinants of effective nasal continuous positive airway (CPAP) pressures were determined in 412 consecutive patients between 1984 and 1989. Patients chosen for analysis had an apnea index (AI) of ≥20 hr-1 prior to CPAP. The AI was 67 ± 30 hr-1, the body mass index (BMI) was 36 ± 9 kg/m2, the age was 51 ± 13 yr and the lowest oxygen saturation was 72 ± 14%. Effective CPAP (9 ± 3 cm H2O) was documented in 320 patients on single night studies and resulted in a 99% reduction in the frequency of obstructive events and improvement in the lowest O2 saturation to 94 ± 5%. Only 18% of the variability in effective CPAP could be explained by AI and BMI. Single night studies are sufficient to establish effective CPAP in 78% of patients and offer considerable conservation of resources compared to routine multiple night studies. Effective CPAP pressures are variable and must be determined by incremental CPAP trials.

Original languageEnglish (US)
Pages (from-to)383-385
Number of pages3
Issue number5
StatePublished - Jan 1 1991


  • Body mass index
  • CPAP
  • Sleep apnea


Dive into the research topics of 'Single night studies in obstructive sleep apnea'. Together they form a unique fingerprint.

Cite this