Single intravenous injection of plasmid DNA encoding human paraoxonase-1 inhibits hyperlipidemia in rats

Keyphrases

• Antioxidant Enzymes 16%
• Cholesterol 16%
• DNA Encoding 100%
• Dyslipidemia 16%
• Hepatic Lipid Accumulation 16%
• High-density Lipoprotein Cholesterol (HDL-C) 16%
• High-fat Diet 16%
• Human Paraoxonase 1 100%
• Hyperlipidemia Model 16%
• Hypertriglyceridemia 33%
• Intravenous Injection 100%
• Low-density Lipoprotein Cholesterol (LDL-C) 33%
• Paraoxonase 1 (PON1) 100%
• Paraoxonase-1 Activity 16%
• Plasmid DNA (pDNA) 100%
• Potential Therapeutics 16%
• Serum Antioxidants 16%
• SOD Activity 16%
• Therapeutic Effect 33%

Biochemistry, Genetics and Molecular Biology

• Animal Models 12%
• Antioxidant Enzyme 12%
• Aryldialkylphosphatase 100%
• Blood Plasma 12%
• Cholesterol Blood Level 12%
• Dyslipidemia 12%
• High-Density Lipoprotein 12%
• Hyperlipidemia 100%
• Hypertriglyceridemia 25%
• Lipid Liver Level 12%
• Lipid Storage 12%
• Low-Density Lipoprotein 25%
• Paraoxonase 100%
• Plasmid 100%
• Rat Model 25%

Pharmacology, Toxicology and Pharmaceutical Science

• Antioxidant 25%
• Aryldialkylphosphatase 1 100%
• Dyslipidemia 12%
• High Density Lipoprotein 12%
• Hyperlipidemia 100%
• Hypertriglyceridemia 25%
• Low Density Lipoprotein Cholesterol 25%
• Plasmid DNA 100%
• Rat Model 25%
• Therapeutic Effect 25%