Single-cell detection of copy number changes reveals dynamic mechanisms of adaptation to antifungals in Candida albicans

Xin Zhou; Audrey Hilk; Norma V. Solis; Nancy Scott; Annette Beach; Natthapon Soisangwan; Clara L. Billings; Laura S. Burrack; Scott G. Filler; Anna Selmecki

doi:10.1038/s41564-024-01795-7

Single-cell detection of copy number changes reveals dynamic mechanisms of adaptation to antifungals in Candida albicans

Xin Zhou, Audrey Hilk, Norma V. Solis, Nancy Scott, Annette Beach, Natthapon Soisangwan, Clara L. Billings, Laura S. Burrack, Scott G. Filler, Anna Selmecki

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Development of a dual-fluorescent reporter system allows rapid quantification of diverse genomic copy number changes that arise in Candida albicans during adaptation to antifungal drugs.

Original language	English (US)
Pages (from-to)	2923-2938
Number of pages	16
Journal	Nature Microbiology
Volume	9
Issue number	11
DOIs	https://doi.org/10.1038/s41564-024-01795-7
State	Published - Nov 2024

Bibliographical note

Publisher Copyright:
© The Author(s), under exclusive licence to Springer Nature Limited 2024..

PubMed: MeSH publication types

Journal Article

Publisher link

10.1038/s41564-024-01795-7

Find It

Find It at U of M Libraries

Cite this

@article{ee70ab4ab0b74a85b63a43991a38d5d3,

title = "Single-cell detection of copy number changes reveals dynamic mechanisms of adaptation to antifungals in Candida albicans",

abstract = "Development of a dual-fluorescent reporter system allows rapid quantification of diverse genomic copy number changes that arise in Candida albicans during adaptation to antifungal drugs.",

author = "Xin Zhou and Audrey Hilk and Solis, {Norma V.} and Nancy Scott and Annette Beach and Natthapon Soisangwan and Billings, {Clara L.} and Burrack, {Laura S.} and Filler, {Scott G.} and Anna Selmecki",

note = "Publisher Copyright: {\textcopyright} The Author(s), under exclusive licence to Springer Nature Limited 2024..",

year = "2024",

month = nov,

doi = "10.1038/s41564-024-01795-7",

language = "English (US)",

volume = "9",

pages = "2923--2938",

journal = "Nature Microbiology",

issn = "2058-5276",

publisher = "Nature Research",

number = "11",

}

TY - JOUR

T1 - Single-cell detection of copy number changes reveals dynamic mechanisms of adaptation to antifungals in Candida albicans

AU - Zhou, Xin

AU - Hilk, Audrey

AU - Solis, Norma V.

AU - Scott, Nancy

AU - Beach, Annette

AU - Soisangwan, Natthapon

AU - Billings, Clara L.

AU - Burrack, Laura S.

AU - Filler, Scott G.

AU - Selmecki, Anna

PY - 2024/11

Y1 - 2024/11

N2 - Development of a dual-fluorescent reporter system allows rapid quantification of diverse genomic copy number changes that arise in Candida albicans during adaptation to antifungal drugs.

AB - Development of a dual-fluorescent reporter system allows rapid quantification of diverse genomic copy number changes that arise in Candida albicans during adaptation to antifungal drugs.

UR - http://www.scopus.com/inward/record.url?scp=85203077634&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85203077634&partnerID=8YFLogxK

U2 - 10.1038/s41564-024-01795-7

DO - 10.1038/s41564-024-01795-7

M3 - Article

C2 - 39227665

AN - SCOPUS:85203077634

SN - 2058-5276

VL - 9

SP - 2923

EP - 2938

JO - Nature Microbiology

JF - Nature Microbiology

IS - 11

ER -

Single-cell detection of copy number changes reveals dynamic mechanisms of adaptation to antifungals in Candida albicans

Abstract

Bibliographical note

PubMed: MeSH publication types

Publisher link

Find It

Other files and links

Fingerprint

Cite this