Simulation of the three-dimensional hinge flow fields of a bileaflet mechanical heart valve under aortic conditions

Hélène A. Simon, Liang Ge, Fotis Sotiropoulos, Ajit P. Yoganathan

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

Thromboembolic complications of bileaflet mechanical heart valves (BMHV) are believed to be due to detrimental stresses imposed on blood elements by the hinge flows. Characterization of these flows is thus crucial to identify the underlying causes for complications. In this study, we conduct three-dimensional pulsatile flow simulations through the hinge of a BMHV under aortic conditions. Hinge and leaflet geometries are reconstructed from the Micro-Computed Tomography scans of a BMHV. Simulations are conducted using a Cartesian sharp-interface immersed-boundary methodology combined with a second-order accurate fractional-step method. Physiologic flow boundary conditions and leaflet motion are extracted from the Fluid-Structure Interaction simulations of the bulk of the flow through a BMHV. Calculations reveal the presence, throughout the cardiac cycle, of flow patterns known to be detrimental to blood elements. Flow fields are characterized by: (1) complex systolic flows, with rotating structures and slow reverse flow pattern, and (2) two strong diastolic leakage jets accompanied by fast reverse flow at the hinge bottom. Elevated shear stresses, up to 1920 dyn/cm2 during systole and 6115 dyn/cm2 during diastole, are reported. This study underscores the need to conduct three-dimensional simulations throughout the cardiac cycle to fully characterize the complexity and thromboembolic potential of the hinge flows.

Original languageEnglish (US)
Pages (from-to)841-853
Number of pages13
JournalAnnals of Biomedical Engineering
Volume38
Issue number3
DOIs
StatePublished - Mar 2010

Bibliographical note

Funding Information:
This work was partially supported by a grant from the National Heart, Lung and Blood Institute (R01-HL-070262), a donation from Tom and Shirley Gur-ley, and the Minnesota Supercomputing Institute.

Keywords

  • Computational fluid dynamics CFD
  • Fluid mechanics
  • Physiologic conditions
  • Pivot
  • Pulsatile numerical simulations

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