TY - JOUR
T1 - SIMPLE TEST FOR CHARACTERIZING SILANOPHILIC INTERACTIONS OF REVERSED-PHASE COLUMNS BASED ON THE CHROMATOGRAPHIC BEHAVIOR OF CYCLIC TETRAAZA COMPOUNDS.
AU - Sadek, Paul C.
AU - Carr, Peter W.
PY - 1983/1/1
Y1 - 1983/1/1
N2 - The silanophilic character of 16 reversed-phase high performance liquid chromatographic columns is evaluated with dimethyldiphenylcyclam, a cyclic tetraaza macrocycle. The method is rapid, does not require the removal of packing material, and uses a water-miscible solvent. The results demonstrate two points: first, cyclic tetraaza macrocycles offer substantial benefits over currently used silanophilic agents; second, the method can easily differentiate the performance of various columns in terms of their relative hydrophobic and silanophilic contributions to solute retention.
AB - The silanophilic character of 16 reversed-phase high performance liquid chromatographic columns is evaluated with dimethyldiphenylcyclam, a cyclic tetraaza macrocycle. The method is rapid, does not require the removal of packing material, and uses a water-miscible solvent. The results demonstrate two points: first, cyclic tetraaza macrocycles offer substantial benefits over currently used silanophilic agents; second, the method can easily differentiate the performance of various columns in terms of their relative hydrophobic and silanophilic contributions to solute retention.
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U2 - 10.1093/chromsci/21.7.314
DO - 10.1093/chromsci/21.7.314
M3 - Article
AN - SCOPUS:0020782953
SN - 0021-9665
VL - 21
SP - 314
EP - 320
JO - Journal of Chromatographic Science
JF - Journal of Chromatographic Science
IS - 7
ER -