Simple and rapid colorimetric detection of p-nitrophenyl substituent organophosphorous nerve agents

Minh Phuong N. Bui, Abdennour Abbas

Research output: Contribution to journalArticlepeer-review

18 Scopus citations

Abstract

We report a very simple and rapid chemical method for the detection of paraoxon and its p-nitrophenyl organophosphorous derivatives. The method uses only sodium borohydride followed by thermal enhancement that increases the sensitivity by two orders of magnitude. Visible, yellow color change of the neurotoxins caused by p-nitrophenolate ions can be rapidly observed at micromolar concentrations while UV-vis measurements enable unprecedented detection at the nanomolar level.

Original languageEnglish (US)
Pages (from-to)370-374
Number of pages5
JournalSensors and Actuators, B: Chemical
Volume207
Issue numberPart A
DOIs
StatePublished - Feb 2015

Bibliographical note

Funding Information:
This work was partially supported by the University of Minnesota MnDRIVE Global Food Venture (Program MNF11 ).

Publisher Copyright:
© 2014 Elsevier B.V. All rights reserved.

Keywords

  • Colorimetric chemical sensor
  • Naked-eye detection
  • Organophosphate neurotoxins
  • Paraoxon
  • p-nitrophenyl

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