Shrink-Induced Highly Sensitive Dopamine Sensor Based on Self-Assembly Graphene on Microelectrode

Guihua Xiao, Jungyoon Kim, Xinxia Cai, Tianhong Cui

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

This paper presents a highly sensitive dopamine microelectrode fabricated by self-assembly of graphene on a gold electrode with polystyrene shrink polymer substrate. Nano graphene wrinkles and gaps are formed on the rough gold layer after shrinkage, significantly enhancing the sensor performance for dopamine detection. Compared with the bare gold electrode, the normalized sensitivity of graphene-shrink electrode improved over 130 times from 0.22 nA•μM-1•mm-2 to 28.77 nA•μM-1•mm-2. The detection limit of dopamine achieved 5 nM, meeting the in-vivo detection requirements. The sensitivity of the shrink electrode increased 23 times from 0.22 nA•μM-1•mm-2 to 5.05 nA•μM-1•mm-2. This simple dopamine sensor with high sensitivity and low detection limit can be widely used in real-time dopamine recording.

Original languageEnglish (US)
Title of host publication2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1120-1123
Number of pages4
ISBN (Electronic)9781728120072
DOIs
StatePublished - Jun 2019
Event20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII - Berlin, Germany
Duration: Jun 23 2019Jun 27 2019

Publication series

Name2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII

Conference

Conference20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII
CountryGermany
CityBerlin
Period6/23/196/27/19

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Keywords

  • Dopamine
  • Graphene
  • High sensitivity
  • Nano wrinkle
  • Shrink

Cite this

Xiao, G., Kim, J., Cai, X., & Cui, T. (2019). Shrink-Induced Highly Sensitive Dopamine Sensor Based on Self-Assembly Graphene on Microelectrode. In 2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII (pp. 1120-1123). [8808235] (2019 20th International Conference on Solid-State Sensors, Actuators and Microsystems and Eurosensors XXXIII, TRANSDUCERS 2019 and EUROSENSORS XXXIII). Institute of Electrical and Electronics Engineers Inc.. https://doi.org/10.1109/TRANSDUCERS.2019.8808235