SHP-1 plays a crucial role in CD40 signaling reciprocity

Keyphrases

• CD40 Signaling 100%
• SHP-1 100%
• CD40 82%
• Phosphorylation 58%
• P38 Mitogen-activated Protein Kinase (p38 MAPK) 35%
• ERK1 29%
• Interleukin-10 17%
• Overexpression 11%
• Feedback System 11%
• Leishmania Major 11%
• C57BL 5%
• Hematopoietic Cells 5%
• Ultra-low Dose 5%
• Syk Inhibition 5%
• Immunomodulatory 5%
• Short Hairpin RNA (shRNA) 5%
• Phosphotyrosine 5%
• Inducible Nitric Oxide Synthase 5%
• Protein Tyrosine Phosphatase 1B (PTP1B) 5%
• CD40 Stimulation 5%
• Infected Macrophages 5%
• Tumor Regression 5%
• Activation Threshold 5%
• Induced Functions 5%
• Functional Duality 5%
• Reverse Effect 5%
• Antileishmanial 5%
• Leishmania Infection 5%
• Balb C Mice 5%

Biochemistry, Genetics and Molecular Biology

• phosphorylation 100%
• Interleukin 10 30%
• Syk 20%
• Macrophage 10%
• Parasite 10%
• C57BL 6 Mouse 10%
• Low Drug Dose 10%
• Bagg Albino Mouse 10%
• Mitogen-Activated Protein Kinase 10%
• Small Hairpin RNA 10%
• Protein Tyrosine Phosphatase 10%
• Leishmania Major 10%
• Nitric Oxide Synthase 10%
• Hematopoietic Cell 10%
• Small Interfering RNA 10%

Immunology and Microbiology

• phosphorylation 100%
• Interleukin 10 30%
• Infectious Disease 10%
• Macrophage 10%
• Low Drug Dose 10%
• Parasite 10%
• C57BL 6 Mouse 10%
• Bagg Albino Mouse 10%
• Hematopoietic Cell 10%
• Leishmaniasis 10%
• Nitric Oxide Synthase 10%
• Infection 10%
• Ribonucleic Acid 10%
• Phosphatase 10%