Should There Be a Recommended Daily Intake of Microbes?

Maria L. Marco, Colin Hill, Robert Hutkins, Joanne Slavin, Daniel J. Tancredi, Daniel Merenstein, Mary Ellen Sanders

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


The collective findings from human microbiome research, randomized controlled trials on specific microbes (i.e., probiotics), and associative studies of fermented dairy consumption provide evidence for the beneficial effects of the regular consumption of safe live microbes. To test the hypothesis that the inclusion of safe, live microbes in the diet supports and improves health, we propose assessment of the types and evidentiary quality of the data available on microbe intake, including the assembly and evaluation of evidence available from dietary databases. Such an analysis would help to identify gaps in the evidence needed to test this hypothesis, which can then be used to formulate and direct initiatives focused on prospective and randomized controlled trials on live microbe consumption. Outcomes will establish whether or not the evidence exists, or can be generated, to support the establishment of dietary recommendations for live microbes.

Original languageEnglish (US)
Pages (from-to)3061-3067
Number of pages7
JournalJournal of Nutrition
Issue number12
StatePublished - Dec 1 2020

Bibliographical note

Publisher Copyright:
© 2020 The Author(s) 2020. Published by Oxford University Press on behalf of the American Society for Nutrition.


  • International Scientific Association for Probiotics and Prebiotics
  • bioactive
  • dietary guidelines
  • fermented food
  • gut microbiome
  • live dietary microbes
  • probiotics

PubMed: MeSH publication types

  • Journal Article


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