Shotgun sequencing of the faecal microbiome to predict response to steroids in patients with lower gastrointestinal acute graft-versus-host disease: An exploratory analysis

Gavin Turner; Madeline Smith; Andrea L Hoeschen; Jessica A. Wilson; Jessica Kennedy; Max Abramson; Qing Cao; Najla El Jurdi; Margaret L. MacMillan; Daniel J. Weisdorf; Bruce R. Blazar; Alexander Khoruts; Robin R Shields-Cutler; Dan Knights; Shernan G. Holtan; Armin Rashidi

doi:10.1111/bjh.17238

Shotgun sequencing of the faecal microbiome to predict response to steroids in patients with lower gastrointestinal acute graft-versus-host disease: An exploratory analysis

Gavin Turner, Madeline Smith, Andrea L Hoeschen, Jessica A. Wilson, Jessica Kennedy, Max Abramson, Qing Cao, Najla El Jurdi, Margaret L. MacMillan, Daniel J. Weisdorf, Bruce R. Blazar, Alexander Khoruts, Robin R Shields-Cutler, Dan Knights, Shernan G. Holtan, Armin Rashidi

Research output: Contribution to journal › Article › peer-review

Original language	English (US)
Pages (from-to)	e69-e73
Journal	British journal of haematology
Volume	192
Issue number	3
DOIs	https://doi.org/10.1111/bjh.17238
State	Published - Nov 22 2020

Bibliographical note

Funding Information:
AR, RRS‐C, GT, MS, DK and QC analyzed the data. AR and RRS‐C wrote the paper. SGH, DK and AK designed the research study. JAW, ALH, MA, JK, NEJ, MLM, DJW, BRB, SGH and AR performed the research study. This study was funded by a grant from Incyte Corp. to AR and a University of Minnesota Grant‐in‐Aid to SGH. AR was supported by the National Institutes of Health’s National Center for Advancing Translational Sciences grant KL2TR002492 and BRB by the National Institute of Allergy and Infectious Diseases grant R37AI34495. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health’s National Center for Advancing Translational Sciences.

Keywords

GVHD
microbiome
transplantation

Publisher link

10.1111/bjh.17238

Find It

Find It at U of M Libraries

Cite this

Turner, G., Smith, M., Hoeschen, A. L., Wilson, J. A., Kennedy, J., Abramson, M., Cao, Q., El Jurdi, N., MacMillan, M. L., Weisdorf, D. J., Blazar, B. R., Khoruts, A., Shields-Cutler, R. R., Knights, D., Holtan, S. G., & Rashidi, A. (2020). Shotgun sequencing of the faecal microbiome to predict response to steroids in patients with lower gastrointestinal acute graft-versus-host disease: An exploratory analysis. British journal of haematology, 192(3), e69-e73. https://doi.org/10.1111/bjh.17238

Shotgun sequencing of the faecal microbiome to predict response to steroids in patients with lower gastrointestinal acute graft-versus-host disease : An exploratory analysis. / Turner, Gavin; Smith, Madeline; Hoeschen, Andrea L et al.

In: British journal of haematology, Vol. 192, No. 3, 22.11.2020, p. e69-e73.

Research output: Contribution to journal › Article › peer-review

Turner, G, Smith, M, Hoeschen, AL, Wilson, JA, Kennedy, J, Abramson, M, Cao, Q , El Jurdi, N , MacMillan, ML , Weisdorf, DJ , Blazar, BR , Khoruts, A, Shields-Cutler, RR, Knights, D , Holtan, SG & Rashidi, A 2020, 'Shotgun sequencing of the faecal microbiome to predict response to steroids in patients with lower gastrointestinal acute graft-versus-host disease: An exploratory analysis', British journal of haematology, vol. 192, no. 3, pp. e69-e73. https://doi.org/10.1111/bjh.17238

@article{e7514863a2cd4f85a3cb8863ff1e073d,

title = "Shotgun sequencing of the faecal microbiome to predict response to steroids in patients with lower gastrointestinal acute graft-versus-host disease: An exploratory analysis",

keywords = "GVHD, microbiome, transplantation",

author = "Gavin Turner and Madeline Smith and Hoeschen, {Andrea L} and Wilson, {Jessica A.} and Jessica Kennedy and Max Abramson and Qing Cao and {El Jurdi}, Najla and MacMillan, {Margaret L.} and Weisdorf, {Daniel J.} and Blazar, {Bruce R.} and Alexander Khoruts and Shields-Cutler, {Robin R} and Dan Knights and Holtan, {Shernan G.} and Armin Rashidi",

note = "Funding Information: AR, RRS‐C, GT, MS, DK and QC analyzed the data. AR and RRS‐C wrote the paper. SGH, DK and AK designed the research study. JAW, ALH, MA, JK, NEJ, MLM, DJW, BRB, SGH and AR performed the research study. This study was funded by a grant from Incyte Corp. to AR and a University of Minnesota Grant‐in‐Aid to SGH. AR was supported by the National Institutes of Health{\textquoteright}s National Center for Advancing Translational Sciences grant KL2TR002492 and BRB by the National Institute of Allergy and Infectious Diseases grant R37AI34495. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health{\textquoteright}s National Center for Advancing Translational Sciences.",

year = "2020",

month = nov,

day = "22",

doi = "10.1111/bjh.17238",

language = "English (US)",

volume = "192",

pages = "e69--e73",

journal = "British Journal of Haematology",

issn = "0007-1048",

publisher = "Wiley-Blackwell",

number = "3",

}

TY - JOUR

T1 - Shotgun sequencing of the faecal microbiome to predict response to steroids in patients with lower gastrointestinal acute graft-versus-host disease

T2 - An exploratory analysis

AU - Turner, Gavin

AU - Smith, Madeline

AU - Hoeschen, Andrea L

AU - Wilson, Jessica A.

AU - Kennedy, Jessica

AU - Abramson, Max

AU - Cao, Qing

AU - El Jurdi, Najla

AU - MacMillan, Margaret L.

AU - Weisdorf, Daniel J.

AU - Blazar, Bruce R.

AU - Khoruts, Alexander

AU - Shields-Cutler, Robin R

AU - Knights, Dan

AU - Holtan, Shernan G.

AU - Rashidi, Armin

N1 - Funding Information: AR, RRS‐C, GT, MS, DK and QC analyzed the data. AR and RRS‐C wrote the paper. SGH, DK and AK designed the research study. JAW, ALH, MA, JK, NEJ, MLM, DJW, BRB, SGH and AR performed the research study. This study was funded by a grant from Incyte Corp. to AR and a University of Minnesota Grant‐in‐Aid to SGH. AR was supported by the National Institutes of Health’s National Center for Advancing Translational Sciences grant KL2TR002492 and BRB by the National Institute of Allergy and Infectious Diseases grant R37AI34495. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health’s National Center for Advancing Translational Sciences.

PY - 2020/11/22

Y1 - 2020/11/22

KW - GVHD

KW - microbiome

KW - transplantation

UR - http://www.scopus.com/inward/record.url?scp=85096659559&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85096659559&partnerID=8YFLogxK

U2 - 10.1111/bjh.17238

DO - 10.1111/bjh.17238

M3 - Article

C2 - 33222185

AN - SCOPUS:85096659559

SN - 0007-1048

VL - 192

SP - e69-e73

JO - British Journal of Haematology

JF - British Journal of Haematology

IS - 3

ER -

Shotgun sequencing of the faecal microbiome to predict response to steroids in patients with lower gastrointestinal acute graft-versus-host disease: An exploratory analysis

Bibliographical note

Keywords

Publisher link

Find It

Other files and links

Cite this