TY - JOUR
T1 - Shortening of the hemodialysis procedure and mortality in ''healthy'' dialysis patients
AU - Collins, Allan J
AU - Kjellstrand, C. M.
PY - 1990/7
Y1 - 1990/7
N2 - The influence of shortening chronic hemodialysis on mortality was studied by following cumulative survival in ''ideal'' nondiabetic dialysis patients, who had no other diseases besides their renal disease when beginning dialysis. It was hoped that thereby problems of shortening dialysis could be separated from problems inherent in the patient. Otherwise healthy dialysis patients (n = 556) were divided into age groups (<50, 51-75, and >75 years) and studied during four periods, 1966-75, 1976-82, 1983-85, and 1986-88. Dialysis time was shortened from 17 to 2.7 hr per treatment during that time, but a Kt/V of 1.3 maintained. Generally, both first- and four-year cumulative survival improved as dialysis was shortened, and four-year cumulative survival was best in all age groups during 1986-88 when dialysis was shortest. During this time, the four-year cumulative survival was no different from that of the age-matched total U.S. population. Shortening of dialysis time and increasing efficiency while keeping at least a 4.0, stable, weekly Kt/V has not been harmful to healthy patients on dialysis, but has led to continued improvement in cumulative survival.
AB - The influence of shortening chronic hemodialysis on mortality was studied by following cumulative survival in ''ideal'' nondiabetic dialysis patients, who had no other diseases besides their renal disease when beginning dialysis. It was hoped that thereby problems of shortening dialysis could be separated from problems inherent in the patient. Otherwise healthy dialysis patients (n = 556) were divided into age groups (<50, 51-75, and >75 years) and studied during four periods, 1966-75, 1976-82, 1983-85, and 1986-88. Dialysis time was shortened from 17 to 2.7 hr per treatment during that time, but a Kt/V of 1.3 maintained. Generally, both first- and four-year cumulative survival improved as dialysis was shortened, and four-year cumulative survival was best in all age groups during 1986-88 when dialysis was shortest. During this time, the four-year cumulative survival was no different from that of the age-matched total U.S. population. Shortening of dialysis time and increasing efficiency while keeping at least a 4.0, stable, weekly Kt/V has not been harmful to healthy patients on dialysis, but has led to continued improvement in cumulative survival.
UR - http://www.scopus.com/inward/record.url?scp=0025453345&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025453345&partnerID=8YFLogxK
M3 - Article
C2 - 2252645
AN - SCOPUS:0025453345
SN - 0889-7190
VL - 36
SP - M145-M148
JO - ASAIO Transactions
JF - ASAIO Transactions
IS - 3
ER -