Shift from stochastic to spatially-ordered expression of serine-glycine synthesis enzymes in 3D microtumors

Keyphrases

• Cancer Cell Lines 40%
• Cell Differences 20%
• Cell Layer 20%
• Cell Line Culture 20%
• Cell-cell Communication 20%
• Cell-to-cell 20%
• Cellular Heterogeneity 20%
• Common Phenomena 20%
• Enzyme Expression 20%
• Glycine 100%
• Growing Cells 20%
• In Cancer 20%
• Intracellular Enzymes 20%
• Mathematical Model 20%
• Metabolic Cancer Therapy 20%
• Metabolic Enzymes 20%
• Metabolic Stress 20%
• Microtumor 100%
• Ordering Patterns 20%
• PHGDH 60%
• Proliferating Cells 20%
• Protein Expression 20%
• Rate-limiting Enzyme 20%
• Structured Environments 20%
• Three-dimensional (3D) 100%
• Tumor 20%

Biochemistry, Genetics and Molecular Biology

• Cancer Cell 66%
• Cell Communication 33%
• Cell Proliferation 33%
• Enzyme 66%
• Enzyme Synthesis 100%
• Phosphoglycerate Dehydrogenase 100%
• Protein Expression 66%
• Serine 100%